Searchable abstracts of presentations at key conferences in endocrinology

ea0020p627 | Reproduction | ECE2009

Isradipine inihibits oxytocin-induced contractions of isolated myometrium from late pregnant rat

Nalbant Mehmet , Kutlu Selim , Kumru Selahattin , Ozcan Mete , Alcin Ergul , Gurates Bilgin , Ayar Ahmet

Preterm labour is a serious clinical problem in obstetrics, and affective treatment of this condition still far from satisfactory. The purpose of this in vitro study was to examine the effects of isradipine, a calcium channel antagonist, on oxytocin-induced contractions of myometrium. Myometral strips were removed from late pregnant (18th day) Wistar rats following decapitation and placed in a jacked tissue bath containing KrebsÂ’ solution and isometric contractions...